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Tag: brain ischemia

Brain ischemia and hypometabolism treated by ozone therapy

This 2011 study evaluated the therapeutic potential of ozone therapy in patients with chronic cerebral ischemia and hypometabolism. Using FDG-PET imaging, researchers demonstrated that ozone therapy significantly improved cerebral glucose metabolism and neurological function. Mechanisms of benefit included enhanced oxygen delivery, improved redox homeostasis, and activation of antioxidant systems. Patients

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June 26, 2025 No Comments

Neurogenesis and neuroprotection in postischemic brain neurodegeneration with Alzheimer phenotype: is there a role for curcumin?

This article reviews the role of curcumin in promoting neurogenesis and providing neuroprotection in the context of brain ischemia and Alzheimer’s disease. It highlights how curcumin may enhance neurogenesis in the hippocampus and prevent neurodegeneration by reducing β-amyloid aggregation, a key factor in Alzheimer’s pathology. Curcumin has shown promise in

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June 26, 2025 No Comments

Neuroprotective and Neurological/Cognitive Enhancement Effects of Curcumin after Brain Ischemia Injury with Alzheimer’s Disease Phenotype

This review discusses the neuroprotective and cognitive enhancement effects of curcumin in the context of brain ischemia and Alzheimer’s disease (AD). It highlights curcumin’s ability to reduce inflammation, improve antioxidant activity, and modulate key proteins linked to Alzheimer’s pathology, such as amyloid precursor protein and tau. The findings suggest that

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June 26, 2025 No Comments

Substantiation for the Use of Curcumin during the Development of Neurodegeneration after Brain Ischemia

The article titled “Substantiation for the Use of Curcumin during the Development of Neurodegeneration after Brain Ischemia” (International Journal of Molecular Sciences, 2020, PMID: 31947633) is a review that explores the potential neuroprotective effects of curcumin in the context of brain ischemia. It highlights curcumin’s antioxidant, anti-inflammatory, and anti-apoptotic properties,

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June 26, 2025 No Comments

Methylene blue and its potential in the treatment of traumatic brain injury, brain ischemia, and Alzheimer’s disease

This article explores the potential therapeutic applications of methylene blue (MB) in treating neurodegenerative conditions like traumatic brain injury, brain ischemia, and Alzheimer’s disease. MB demonstrates multiple beneficial effects, including anti-apoptotic and anti-inflammatory actions, inhibition of protein aggregation, activation of autophagy, and modulation of mitochondrial function. These properties suggest that

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June 26, 2025 No Comments