Methylene blue attenuates neuroinflammation after subarachnoid hemorrhage in rats through the Akt/GSK-3β/MEF2D signaling pathway
This study evaluated the neuroprotective effects of methylene blue (MB) in rats following subarachnoid hemorrhage (SAH), focusing on its ability to reduce neuroinflammation. MB treatment significantly decreased brain edema and improved neurological function by activating the Akt/GSK-3β/MEF2D signaling pathway, which led to increased nuclear MEF2D levels. Additionally, MB reduced pro-inflammatory
June 26, 2025
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