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Tag: Brain-derived neurotrophic factor

Beneficial action of resveratrol: How and why?

This review article explores the wide-ranging health benefits of resveratrol, focusing on its anti-inflammatory, anticancer, and neuroprotective properties. Resveratrol modulates several biological pathways, including NF-κB, cyclooxygenase enzymes, apoptosis pathways, and the AMPK pathway, leading to its beneficial effects on inflammation, metabolism, and neurological health. The article highlights resveratrol’s potential in

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June 26, 2025 No Comments

Methylene blue protects dopaminergic neurons against MPTP-induced neurotoxicity by upregulating brain-derived neurotrophic factor

This study investigates the neuroprotective effects of methylene blue (MB) in Parkinson’s disease (PD) models, revealing that MB prevents dopaminergic neuron loss and mitigates dopamine depletion by upregulating brain-derived neurotrophic factor (BDNF) and activating Erk signaling pathways. The results highlight that MB’s protective role is associated with BDNF activation, which

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June 26, 2025 No Comments

Carbohydrate-restricted Diet and Exercise Increase Brain-derived Neurotrophic Factor and Cognitive Function: A Randomized Crossover Trial

This study examined the effects of a carbohydrate-restricted diet (CRPD) combined with high-intensity interval training (HIIT) on cognitive function and brain-derived neurotrophic factor (BDNF) levels in individuals with metabolic syndrome (MetS). The results showed significant improvements in cognitive performance, such as psychomotor speed and cognitive flexibility, along with a 20%-38%

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June 26, 2025 No Comments