Complementary roles in cancer prevention: protease inhibitor makes the cancer preventive peptide lunasin bioavailable
This study examines the role of the Bowman-Birk protease inhibitor (BBI) in enhancing the oral bioavailability and cancer-preventive activity of lunasin, a soy-derived peptide known for its epigenetic modulation properties. Lunasin binds to deacetylated histones and inhibits histone acetylation, thereby regulating gene expression involved in tumorigenesis. However, its effectiveness is
June 26, 2025
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