blood pressure regulation Archives

Peripheral and Central Effects of Melatonin on Blood Pressure Regulation

This 2014 review examines melatonin’s role in blood pressure regulation through both peripheral and central mechanisms. Peripherally, melatonin interacts with MT1 and MT2 receptors, leading to vasodilation, and exerts antioxidant effects by scavenging reactive oxygen species and enhancing mitochondrial efficiency. Centrally, it modulates autonomic balance by reducing sympathetic activity and

June 26, 2025 No Comments

Magnesium inhibits norepinephrine release by blocking N-type calcium channels at peripheral sympathetic nerve endings

This in vitro and animal study explored the role of magnesium in regulating blood pressure by examining its effect on norepinephrine release from sympathetic nerve endings. Using hypertensive and normotensive rat models, as well as cultured PC12 cells, researchers found that magnesium significantly inhibited norepinephrine release—reducing it by 51% in

June 26, 2025 No Comments

Oral arginine improves blood pressure in renal transplant and hemodialysis patients

The study titled Oral Arginine Improves Blood Pressure in Renal Transplant and Hemodialysis Patients (JPEN J Parenter Enteral Nutr, 2001, PMID: 11434650) is a clinical trial examining the effects of oral arginine supplementation on blood pressure in hypertensive renal transplant and hemodialysis patients. Results showed that oral arginine, with or

June 26, 2025 No Comments

Well Referenced

Tag: blood pressure regulation

Peripheral and Central Effects of Melatonin on Blood Pressure Regulation

Magnesium inhibits norepinephrine release by blocking N-type calcium channels at peripheral sympathetic nerve endings

Oral arginine improves blood pressure in renal transplant and hemodialysis patients