Tag: Bisphosphonates

Ocular Side Effects of Bisphosphonates: A Review of Literature

This 2023 review analyzed 101 reports of bisphosphonate-associated ocular complications, including uveitis, scleritis, episcleritis, conjunctivitis, and orbital inflammation. These adverse effects are primarily linked to second- and third-generation amino bisphosphonates such as alendronate, pamidronate, risedronate, and zoledronate, with intravenous forms posing a higher risk and more rapid onset than oral

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Beyond aspirin-cancer prevention with statins, metformin and bisphosphonates

This article reviews the potential role of statins, metformin, and bisphosphonates in cancer prevention. The study examines the mechanisms by which these agents, commonly used for cardiovascular, metabolic, and bone health, may reduce cancer risk. Statins may inhibit tumor growth by targeting cholesterol synthesis pathways, metformin by affecting insulin and

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Hormone replacement in women with a history of breast cancer

This review discusses hormone replacement therapy (HRT) and estrogen replacement therapy (ERT) for women with a history of breast cancer, emphasizing the challenges and risks due to concerns about cancer recurrence. While HRT and ERT are effective for managing menopausal symptoms, the review highlights alternative treatments like SSRIs (e.g., venlafaxine),

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