Tag: Biological Aging

Telomere Length Maintenance and Cardio-Metabolic Disease Prevention Through Exercise Training

This 2016 review article examines the relationship between physical activity and telomere dynamics, highlighting how exercise can prevent telomere shortening—a key marker of biological aging—and reduce the risk of cardio-metabolic diseases. The authors discuss molecular mechanisms by which exercise influences telomere length, including the upregulation of telomerase activity and reduction

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A new aging measure captures morbidity and mortality risk across diverse subpopulations from NHANES IV: A cohort study

This 2018 cohort study introduced “Phenotypic Age,” a composite biomarker derived from chronological age and nine clinical chemistry markers, to estimate biological aging and associated mortality risk. Utilizing data from NHANES IV (1999–2010), the study analyzed 11,432 adults aged 20–84 and 185 adults aged 85 and older. Findings revealed that

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