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Tag: bioidentical hormones

The bioidentical hormone debate: are bioidentical hormones (estradiol, estriol, and progesterone) safer or more efficacious than commonly used synthetic versions in hormone replacement therapy?

A review published in Postgraduate Medicine examined the safety and efficacy of bioidentical hormones (progesterone, estradiol, and estriol) compared to synthetic and animal-derived hormones used in hormone replacement therapy (HRT). The study found that patients reported greater satisfaction with HRT containing bioidentical progesterone over synthetic progestins. Clinical and physiological data

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June 26, 2025 No Comments

Compounded Bioidentical Hormones in Endocrinology Practice: An Endocrine Society Scientific Statement

The Endocrine Society’s statement cautions against the use of compounded bioidentical hormone therapy (cBHT), citing the lack of regulation and evidence supporting its safety and efficacy. They advise endocrinologists to prioritize FDA-approved hormone treatments instead. This review emphasizes the potential risks of unregulated therapies and urges practitioners to prioritize safety.

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June 26, 2025 No Comments

Compounded Bioidentical Hormones: Myths and Realities

This article explores the widespread use of compounded bioidentical hormone therapy (cBHT), highlighting the lack of rigorous scientific evidence supporting its safety and efficacy. It stresses the need for clinicians to guide patients toward FDA-approved treatments for menopausal symptoms rather than relying on unregulated compounded alternatives. The article emphasizes the

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June 26, 2025 No Comments

Bioidentical hormone therapy in menopause: relevance in dermatology

This review article discusses the use of bioidentical hormone therapy (BHT) for managing menopausal symptoms and its application in dermatology. BHT, designed to mimic natural hormones, is widely marketed for its potential skin benefits, such as anti-aging effects. However, there is limited scientific evidence supporting these claims, and dermatologists are

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June 26, 2025 No Comments

Bioidentical hormone therapy: a review

This review evaluates bioidentical hormone therapy (BHT) for managing menopausal symptoms, comparing it to conventional hormone replacement therapy (HRT). While BHT may alleviate symptoms for some, evidence supporting its efficacy and safety is limited, and there is no clear advantage over traditional HRT. The review also highlights concerns with individualized

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June 26, 2025 No Comments

Bioidentical hormones for menopausal therapy

This review discusses the use of bioidentical hormones for menopausal therapy, criticizing the assumption that they are safer than synthetic hormones. Despite some proponents advocating for their use, particularly through salivary hormone testing, the review finds insufficient evidence to support their superiority or safety compared to synthetic options. Providers should

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June 26, 2025 No Comments

Bioidentical hormones for women with vasomotor symptoms

A 2016 systematic review published in The Cochrane Database of Systematic Reviews (PMID: 27479272) evaluated the efficacy and safety of bioidentical hormone therapy (BHT) for menopausal vasomotor symptoms. Analyzing randomized controlled trials comparing BHT to placebo or conventional hormone therapy, the study found that 17β-estradiol effectively reduced the frequency and

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June 26, 2025 No Comments

Bioidentical hormones, menopausal women, and the lure of the “natural” in U.S. anti-aging medicine

The study titled “Bioidentical hormones, menopausal women, and the lure of the ‘natural’ in U.S. anti-aging medicine” (Social Science & Medicine, 2015, PMID: 25795991) is an observational study examining the perspectives of 31 U.S.-based anti-aging clinicians and 25 female patients on bioidentical hormone replacement therapy (BHRT). The research highlights that

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June 26, 2025 No Comments

Absorption of Oral Progesterone is Influenced by Vehicle and Particle Size

This clinical trial examined how oral progesterone absorption is influenced by formulation, specifically particle size and vehicle type. Seven subjects received a 200 mg dose of progesterone in different formulations: plain milled, micronized, plain milled in oil, micronized in oil, and micronized in enteric-coated capsules. Serum progesterone levels were measured

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June 26, 2025 No Comments