Well Referenced

Tag: benign prostatic hyperplasia

Correction: The UroLift implant: mechanism behind rapid and durable relief from prostatic obstruction

This 2022 correction pertains to the original article discussing the UroLift implant, a minimally invasive treatment for benign prostatic hyperplasia (BPH). The UroLift system employs small implants to retract prostatic tissue, thereby relieving urethral obstruction without cutting or removing tissue. This approach offers rapid symptom relief and preserves sexual function.

Read More »
June 26, 2025 No Comments

Novel Actions of Progesterone: What We Know Today and What Will Be the Scenario in the Future?

This 2012 review highlights emerging non-reproductive roles of progesterone, including potential therapeutic applications in traumatic brain injury (TBI), stroke, Alzheimer’s disease, diabetic neuropathy, and crush injuries. Preclinical and early clinical studies suggest that progesterone and its derivatives, such as norethisterone and megestrol acetate, may offer neuroprotective and anti-inflammatory benefits. Additionally,

Read More »
June 26, 2025 No Comments

A new look at the 5alpha-reductase inhibitor finasteride

This 2006 review published in CNS Drug Reviews (PMID: 16834758) evaluates the broader pharmacological effects of finasteride, a 5α-reductase inhibitor used to treat benign prostatic hyperplasia and androgenetic alopecia. Beyond reducing dihydrotestosterone (DHT), finasteride alters the metabolism of neuroactive steroids like allopregnanolone, impacting GABAergic neurotransmission. These neurosteroid shifts have been

Read More »
June 26, 2025 No Comments

Post-finasteride syndrome: a surmountable challenge for clinicians

This review article explores Post-Finasteride Syndrome (PFS), a condition characterized by persistent sexual, neurological, physical, and psychological side effects that can occur during or after discontinuation of finasteride or dutasteride, commonly prescribed for androgenetic alopecia or benign prostatic hyperplasia. The review identifies significant adverse effects such as sexual dysfunction, depression,

Read More »
June 26, 2025 No Comments