Well Referenced

Tag: behavioral therapy

One-Year Behavioral Treatment of Obesity: Comparison of Moderate and Severe Caloric Restriction and the Effects of Weight Maintenance Therapy

This randomized controlled trial evaluated 49 obese women over a 52-week behavioral program, comparing a balanced deficit diet (BDD; 1,200 kcal/day) with a very-low-calorie diet (VLCD; 420 kcal/day for 16 weeks, then 1,200 kcal/day). At 26 weeks, the VLCD group achieved greater weight loss (mean 21.45 kg) than the BDD

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June 26, 2025 No Comments

Nutraceutical and Other Modalities for the Treatment of Headache

This 2015 review by Stewart J. Tepper evaluates the evidence supporting nutraceutical, biobehavioral, and physical treatments for migraine and other headache disorders. For migraine prevention in adults, Level B evidence supports the use of feverfew, magnesium, and riboflavin (vitamin B2). Coenzyme Q10 (CoQ10) has Level C evidence, while melatonin has

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June 26, 2025 No Comments

Multicenter, Placebo-Controlled Trial of Lorcaserin for Weight Management

This 2010 double-blind, randomized controlled trial (BLOOM) evaluated the efficacy and safety of lorcaserin, a selective 5-HT₂C receptor agonist, in 3,182 overweight or obese adults over 52 weeks. Participants received lorcaserin 10 mg twice daily or placebo, alongside lifestyle counseling. At 1 year, 47.5% of the lorcaserin group lost ≥5%

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June 26, 2025 No Comments

Randomized trial of lifestyle modification and pharmacotherapy for obesity

This 2005 randomized, controlled trial assessed the efficacy of combining sibutramine (15 mg daily) with lifestyle modification in 224 obese adults over one year. Participants were assigned to one of four groups: sibutramine alone, lifestyle modification alone, sibutramine plus lifestyle modification, or sibutramine plus brief lifestyle counseling. All groups followed

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June 26, 2025 No Comments