This 1996 review by I.M. Jackson evaluates the evidence supporting the use of thyroid hormones—particularly triiodothyronine (T3)—as adjunctive therapy in depression. The review highlights that hypothyroidism is commonly associated with depressive symptoms and should be treated with levothyroxine (T4). T3 has been shown to accelerate or enhance the response to
This 2018 systematic review and meta-analysis evaluated the link between autoimmune thyroiditis (AIT) and mood disorders, specifically depression and anxiety. The analysis included 19 studies comprising over 36,000 individuals. Results showed that patients with AIT, including Hashimoto’s thyroiditis, had a 3.56-fold increased odds of depression and a 2.32-fold increased odds
The study examines the role of nutrition in thyroid disease management, focusing on the impact of essential micronutrients such as iodine, selenium, iron, zinc, and vitamins B12, D3, and A on thyroid function. It highlights the benefits of the Mediterranean diet in improving immune, endocrine, and biomolecular responses in thyroiditis
