Tag: Autoimmune Disorders

A Double-Blind, Cross-Over, Study of Oral N-Acetylcysteine in Sjögren’s Syndrome

This 1986 double-blind, cross-over trial evaluated the efficacy of oral N-acetylcysteine (NAC) in 26 patients with primary or secondary Sjögren’s syndrome over a four-week period. Baseline assessments revealed significantly elevated salivary lactoferrin levels and decreased tear lysozyme levels compared to healthy controls. Following NAC treatment (200 mg three times daily),

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Alpha lipoic acid inhibits T cell migration into the spinal cord and suppresses and treats experimental autoimmune encephalomyelitis

The study “Alpha Lipoic Acid Inhibits T Cell Migration into the Spinal Cord and Suppresses and Treats Experimental Autoimmune Encephalomyelitis” examined the effects of alpha lipoic acid (ALA) on experimental autoimmune encephalomyelitis (EAE), a mouse model of multiple sclerosis (MS). Administering ALA at doses of 5-100 mg/kg/day significantly reduced disease

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Analysis of the clinical characteristics of insulin autoimmune syndrome induced by alpha-lipoic acid

The study titled “Analysis of the clinical characteristics of insulin autoimmune syndrome induced by alpha-lipoic acid” (Journal of Clinical Pharmacy and Therapeutics, 2021, PMID: 33821530) investigated 37 patients (28 females, 9 males, median age 61) who developed insulin autoimmune syndrome (IAS) after taking alpha-lipoic acid (ALA). Symptoms of hypoglycemia primarily

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