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Tag: ARDS

Serious Adverse Events of Cell Therapy for Respiratory Diseases: A Systematic Review and Meta-Analysis

This systematic review and meta-analysis assessed the safety profile of cell-based therapies in respiratory diseases by analyzing 23 clinical studies involving 204 patients with conditions such as ARDS, COPD, IPF, PAH, and others. The findings indicated that both systemic infusions and bronchial instillations of mesenchymal stem/stromal or progenitor cells were

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June 26, 2025 No Comments

Thymosin alpha-1

Thymosin alpha-1 (Tα1) is a synthetic peptide derived from thymic tissue, recognized for its immunomodulatory properties. It enhances T-cell differentiation and function, augments natural killer (NK) cell activity, and modulates cytokine production. Clinically, Tα1 has been approved in over 30 countries for treating chronic hepatitis B and C, and has

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June 26, 2025 No Comments

Therapeutic potential of products derived from mesenchymal stem/stromal cells in pulmonary disease

This 2018 review article explores the therapeutic potential of mesenchymal stem/stromal cell (MSC)-derived products, particularly conditioned media (CM) and extracellular vesicles (EVs), in treating pulmonary diseases. MSCs are known for their regenerative and immunomodulatory properties, which are largely mediated through their secretome. The review highlights preclinical studies demonstrating the efficacy

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June 26, 2025 No Comments