Tag: anti-inflammatory strategies​

Inflamm-ageing: the role of inflammation in age-dependent cardiovascular disease

This review discusses the concept of “inflamm-ageing,” a chronic low-grade inflammation associated with aging that contributes to vascular aging, atherosclerosis, and age-related cardiovascular diseases (CVDs). It highlights how inflammasome activation and reduced anti-inflammatory mechanisms accelerate vascular dysfunction, and it suggests that targeting these inflammatory pathways may help prevent or treat

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Low-Grade Chronic Inflammation: a Shared Mechanism for Chronic Diseases

This 2025 review article published in Physiology (Bethesda) (DOI: 10.1152/physiol.00021.2024) explores low-grade chronic inflammation (LGCI) as a central mechanism underlying a wide range of chronic diseases, including obesity, cardiovascular conditions, digestive disorders, and cancer. It explains that unresolved or persistent inflammatory stimuli can result in LGCI, which in turn promotes

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