From French Paradox to cancer treatment: anti-cancer activities and mechanisms of resveratrol
This comprehensive review explores the anti-cancer properties of resveratrol, a polyphenolic compound found in grapes and red wine. Resveratrol exerts its effects through multiple mechanisms, including induction of apoptosis via p53 activation, inhibition of NF-κB signaling, modulation of the PI3K/Akt pathway, and suppression of angiogenesis through VEGF downregulation. It also