Bipolar Androgen Therapy: A Paradoxical Approach for the Treatment of Castration-resistant Prostate Cancer
This 2017 editorial discusses bipolar androgen therapy (BAT) as a novel treatment strategy for castration-resistant prostate cancer (CRPC). BAT involves alternating testosterone levels between supraphysiologic and near-castrate concentrations, aiming to exploit the paradoxical effects of androgen exposure on tumor cells. Initial studies have shown that BAT is safe and can
June 26, 2025
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