Tag: amino acid metabolism

1H NMR-based metabolomic study of metabolic profiling for pollinosis

This 2019 study utilized proton nuclear magnetic resonance (^1H NMR) spectroscopy to analyze serum samples from 37 patients with pollinosis (seasonal allergic rhinitis) during symptomatic (seizure) and asymptomatic (remission) phases. The analysis revealed significant metabolic alterations during the symptomatic phase, including decreased levels of branched-chain amino acids (isoleucine, leucine, valine),

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Glutamine is a key regulator for amino acid-controlled cell growth through the mTOR signaling pathway in rat intestinal epithelial cells

The 2005 study titled “Glutamine is a key regulator for amino acid-controlled cell growth through the mTOR signaling pathway in rat intestinal epithelial cells” (PMID: 15567168) explores the role of glutamine in regulating cellular growth via the mammalian target of rapamycin (mTOR) signaling pathway. Conducted in rat intestinal epithelial cells,

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Impact of combined resistance and aerobic exercise training on branched-chain amino acid turnover, glycine metabolism and insulin sensitivity in overweight humans

This randomized controlled trial published in Diabetologia (2015) examined the effects of combined resistance and aerobic exercise training on insulin sensitivity, branched-chain amino acid (BCAA) metabolism, and glycine levels in overweight adults. Over a 6-month period, sedentary participants with a BMI ≥25 (n=119) followed a supervised exercise protocol. The study

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