1H NMR-based metabolomic study of metabolic profiling for pollinosis
This 2019 study utilized proton nuclear magnetic resonance (^1H NMR) spectroscopy to analyze serum samples from 37 patients with pollinosis (seasonal allergic rhinitis) during symptomatic (seizure) and asymptomatic (remission) phases. The analysis revealed significant metabolic alterations during the symptomatic phase, including decreased levels of branched-chain amino acids (isoleucine, leucine, valine),