Alternative mitochondrial electron transfer as a novel strategy for neuroprotection
Methylene blue (MB) demonstrates neuroprotective potential by acting as an alternative electron carrier in the mitochondrial electron transport chain, bypassing dysfunctions in complexes I and III. This mechanism enhances mitochondrial respiration, reduces reactive oxygen species, and prevents cellular energy failure. In animal models of Parkinson’s disease and cerebral ischemia, MB
June 26, 2025
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