High-grade Prostate Cancer and Biochemical Recurrence After Radical Prostatectomy Among Men Using 5α-Reductase Inhibitors and Alpha-Blockers
This 2013 cohort study analyzed 1,315 men who underwent radical prostatectomy between 1995 and 2009 to assess the impact of 5α-reductase inhibitors (5-ARIs) and alpha-blockers on tumor grade and biochemical recurrence. Long-term use (≥4 years) of 5-ARIs (finasteride or dutasteride) was associated with a higher proportion of high-grade tumors (Gleason
June 26, 2025
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