Tag: Aging Mechanism

Telomere shortening is a sole mechanism of aging in mammals

This 2012 review by Mikhelson and Gamaley posits that telomere shortening is the primary driver of aging in mammals. The authors argue that telomere attrition occurs with each cell division due to the DNA replication process, independent of oxidative damage. They contend that even in the absence of oxidative stress,

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