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Tag: age-related hearing loss

Higher serum aldosterone correlates with lower hearing thresholds: a possible protective hormone against presbycusis

This cross-sectional study assessed 47 adults aged 58–84 to determine whether higher serum aldosterone levels are associated with better hearing function. Audiometric evaluations included pure-tone thresholds, hearing in noise test (HINT), transient evoked otoacoustic emissions (TEOAE), and gap detection. Results demonstrated a significant correlation between elevated aldosterone levels and improved

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June 26, 2025 No Comments

Physiological and neurobiological bases of age-related hearing loss: biotherapeutic implications

This comprehensive review examines the cellular, molecular, and hormonal factors contributing to age-related hearing loss (presbycusis), particularly the roles of sex hormones (estrogen, progesterone) and aldosterone in auditory aging. Estrogen appears to exert neuroprotective effects on auditory function, whereas progesterone may impair it. Aldosterone has been shown to enhance potassium

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June 26, 2025 No Comments

Maintaining good hearing: calorie restriction, Sirt3, and glutathione

This review examines how calorie restriction (CR) can slow the progression of age-related hearing loss (AHL), a common aging condition linked to the degeneration of sensory hair cells, spiral ganglion neurons, and the stria vascularis in the cochlea. The study highlights mitochondrial Sirt3, a sirtuin protein, as a critical mediator

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June 26, 2025 No Comments