Tag: acute coronary syndrome

Low-Dose Colchicine for the Prevention of Cardiovascular Events After Acute Coronary Syndrome

This 2024 review article explores the role of low-dose colchicine (0.5 mg daily) as an anti-inflammatory therapy in reducing adverse cardiovascular events following acute coronary syndrome (ACS). Colchicine exerts its effects by inhibiting microtubule polymerization, thereby reducing leukocyte activation and inflammatory responses implicated in atherosclerotic plaque destabilization. Clinical trials, including

Read More »

Homocysteine and markers of inflammation in acute coronary syndrome

This observational study examined the associations between elevated total homocysteine (tHcy) levels, inflammatory markers (HsCRP, IL-6, TNFα), and coronary artery disease (CAD) severity in acute coronary syndrome (ACS) patients. The researchers found higher levels of tHcy, HsCRP, and proinflammatory cytokines correlated with an increased number of diseased vessels, while folate

Read More »