This 1990 single-blind, randomized clinical trial evaluated the efficacy and skin tolerance of 5% tea-tree oil (TTO) gel compared to 5% benzoyl peroxide (BP) lotion in 124 patients with mild to moderate acne. Both treatments significantly reduced the number of inflamed and non-inflamed lesions, including open and closed comedones. However,
A review article titled Photobiomodulation CME Part II: Clinical Applications in Dermatology discusses the use of photobiomodulation (PBM), a noninvasive light therapy using red (620-700 nm) and near-infrared (700-1440 nm) light, for various dermatological conditions. PBM, delivered through low-level lasers or light-emitting diodes, has been shown to effectively treat side
This review explores the clinical applications of photobiomodulation (PBM), or low-level light therapy (LLLT), in dermatology and regenerative medicine, highlighting its role in enhancing mitochondrial ATP production, modulating oxidative stress, and promoting cell signaling for tissue repair. PBM has shown potential in improving skin appearance, treating acne vulgaris, accelerating wound
his systematic review and meta-analysis evaluated the efficacy of light-emitting diode (LED) therapy for dermatological conditions, analyzing 31 studies with 1,230 participants aged 18 to 65. The findings demonstrated significant improvements in acne, psoriasis, wound healing, and skin rejuvenation. Red and blue LED treatments reduced acne lesions by 52% (p
This in vitro study investigated the potential DNA-damaging effects of visible red light (RL) exposure on human dermal fibroblasts (HDFs), given its growing use in dermatology for acne, psoriasis, and wound healing. The study found that RL at fluences of 320 J/cm², 640 J/cm², and 1280 J/cm² (wavelength 633 ± 6 nm) did
A review published in Seminars in Cutaneous Medicine and Surgery (2013) explored the applications and mechanisms of low-level laser (light) therapy (LLLT) in dermatology. LLLT, also known as photobiomodulation, utilizes red and near-infrared light to stimulate healing, alleviate pain and inflammation, and restore skin function. It has shown efficacy in
This observational study evaluated the effectiveness of narrowband blue light therapy (409-419 nm) for mild to moderate facial acne in 30 participants. Over four weeks, subjects received eight treatment sessions, with assessments at weeks 5, 8, and 12. The study found a significant reduction in inflammatory acne lesions by week
