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Tag: 8-hydroxydeoxyguanosine

Occupational and lifestyle factors and urinary 8-hydroxydeoxyguanosine

This observational study examined the impact of occupational and lifestyle factors on urinary 8-hydroxydeoxyguanosine (8-OHdG) levels, a biomarker of oxidative DNA damage. Findings indicated that individuals with specific occupational exposures to hazardous substances or certain lifestyle behaviors exhibited higher 8-OHdG concentrations, suggesting increased oxidative stress. Monitoring urinary 8-OHdG provides a

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June 26, 2025 No Comments

Effect of age, smoking and other lifestyle factors on urinary 7-methylguanine and 8-hydroxydeoxyguanosine

This observational study examined the effects of age, smoking, and other lifestyle factors on urinary levels of 7-methylguanine (m7G) and 8-hydroxydeoxyguanosine (8-OHdG), biomarkers of DNA methylation and oxidative DNA damage, respectively. Analyzing 215 healthy Japanese individuals, the study found that current smokers exhibited significantly higher urinary m7G levels (p <

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June 26, 2025 No Comments

Oxidative stress biomarkers and lifestyles in Japanese healthy people

This observational study investigated the relationship between lifestyle factors and oxidative stress biomarkers in 135 healthy Japanese adults aged 20 to 69 years. The findings showed that smokers had significantly higher urinary 8-hydroxydeoxyguanosine (8-OHdG) levels (p < 0.05), indicating increased oxidative DNA damage, while individuals who engaged in regular physical

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June 26, 2025 No Comments

Oxidative DNA damage estimated by 8-hydroxydeoxyguanosine excretion in humans: influence of smoking, gender and body mass index

This observational study examined the relationship between oxidative DNA damage, measured by urinary 8-hydroxydeoxyguanosine (8-OHdG) excretion, and lifestyle factors such as smoking, gender, and body mass index (BMI) in 121 healthy individuals aged 25-64. Results showed that smokers had a 50% higher 8-OHdG excretion than non-smokers (p

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June 26, 2025 No Comments

Urinary 8-OHdG: a marker of oxidative stress to DNA and a risk factor for cancer, atherosclerosis and diabetics

This study explores the role of urinary 8-hydroxydeoxyguanosine (8-OHdG) as a biomarker for oxidative stress and its association with increased risks of cancer, atherosclerosis, and diabetes. Elevated urinary 8-OHdG levels were observed in patients with various cancers, human atherosclerotic plaques, and diabetic individuals with hyperglycemia, highlighting its potential as a

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June 26, 2025 No Comments