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Tag: β-amyloid

Association of Proton Pump Inhibitors With Risk of Dementia: A Pharmacoepidemiological Claims Data Analysis

This 2016 prospective cohort study analyzed data from 73,679 German individuals aged 75 and older, free of dementia at baseline, to investigate the association between proton pump inhibitor (PPI) use and incident dementia. Regular PPI use (defined as at least one prescription per quarter over 18 months) was associated with

June 26, 2025 No Comments

Role of metals in Alzheimer’s disease

This 2021 review examines the involvement of metal ions—specifically aluminum, iron, copper, and zinc—in the pathogenesis of Alzheimer’s disease (AD). It discusses how these metals contribute to the formation of extracellular β-amyloid plaques and intracellular neurofibrillary tau tangles, hallmark features of AD. The review also evaluates the therapeutic potential of

June 26, 2025 No Comments