Induction of fat cell necrosis in human fat tissue after treatment with phosphatidylcholine and deoxycholate

This 2012 study investigated the effects of phosphatidylcholine (PC) and deoxycholate (DC) injections on human adipose tissue. Histological analysis revealed that the treatment induced fat cell necrosis rather than apoptosis. The findings suggest that the fat-reducing effects are due to nonspecific cell and tissue destruction, raising concerns about the safety