High-dose Parenteral Ascorbate Enhanced Chemosensitivity of Ovarian Cancer and Reduced Toxicity of Chemotherapy

This study investigated the effects of high-dose intravenous vitamin C (ascorbate) on the sensitivity of ovarian cancer to chemotherapy and its potential to reduce chemotherapy-induced toxicity. The research involved both in vitro (cell culture) and in vivo (animal model) experiments. The findings suggested that pharmacologic concentrations of ascorbate can enhance